- Islandora Repository
- Text Collection
- American Physical Society and APS. Joint Committee on the History of Theoretical Physics in the Twentieth Century. Collection
- An Annotated Calendar of the Letters of Charles Darwin in the Library of the American Philosophical Society
- An historical and chronological description of two stones found under ground, in the great square of the City of Mexico, in the years 1790 [translation]
- An inaugural disputation, concerning the varieties of the human race, July 1800, 1830
- Anathan-Jacobs Grand Trunk Pacific Railway Collection
- Andre, Major John, Letter Regarding the Battle of Germantown
- André Michaux letters and papers, 1783-1890
- Anne Roe papers, 1949-1974 (bulk)
- Anniversary oration delivered ... before the American Philosophical Society ... for ...1782
- Apollo 11 Mission Commentary
- Arawak manuscripts
- Arte y vocabulario de la lengua Cholti, 1695